Generics: Oxymetazoline Hydrochloride
Dosage Form: Nasal Spray.
Oxymetazoline Hydrochlorid is indicated for the treatment of nasal congestion associated with acute or chronic rhinitis, common cold, sinusitis, upper respiratory allergies, epistaxis and hay fever. It is also used as nasal decongestant in otitis media.
Oxymetazoline Hydrochloride is a sympathomimetic amine that is derived from imidazoline. It acts as a direct agonist on -adrenoceptors but not on -adrenoceptors. When applied topically to the nasal mucosa, it causes a quick and long-acting vasoconstriction of the arterioles, which reduces blood flow and reduces mucosal edema. As a result, the airway’s potency improves, and the nasal sinuses drain more effectively.
- Oxymetazoline nasal spray-
Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
Elderly: There is no need for dosage reduction in the elderly for nasal administration.
Children below 6 years of age: It is not suitable for children below 6 years of age.
- Oxymetazoline nasal drop-
Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening
Route of administration: Intrnasal.
Oxymetazoline Hydrochloride Nasal preparation should not be given to patients being treated with MAO inhibitors or within 14 days of ceasing such treatment.
It is contraindicated in patients with cardiovascular disease, hyperthyroidism, prostatic enlargement, angle closure glaucoma and hypersensitivity to any of its ingredients.
Occasionally it may cause local irritation and dryness of the mouth and throat. Temporarily discomfort such as burning, stinging, sneezing or increase in nasal discharge may occur.
Pregnancy & Lactation:
The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and lactation has not been established, but is not thought to constitute a hazard during those periods.
Precautions & Warnings:
Keep away from the eyes. The spray should not be used for longer than seven days without medical advice. Frequent or prolonged use may cause nasal congestion to recur or worsen.
Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations
Keep below 30° C temperature in a dry place, protect from light. Do not refrigerate or freeze. Keep out of the reach of children.
Manufactured by: Aristopharma Ltd.