Description
Generics: Testosterone undecanoate
Dosage Form: Tablet.
Indications:
The active substance of this preparation is turned into testosterone by your body. Testosterone is the natural male hormone, necessary for the normal growth, development and function of the male sex organs and for secondary male sex characteristics. Preparations containing Testosterone are usually prescribed to replace the hormone if the body is unable to produce enough on its own. Testosterone are soft oval glossy capsules, transparent, orange-red colour, with an oily fill.
Pharmacology:
Testosterone is involved in the regulation of hematopoiesis, body composition, and bone metabolism in men and plays a vital role in sexual differentiation. As a result, testosterone replacement therapy for hypogonadism in men can lead to better sexual performance, increased lean body mass, bone density, erythropoiesis, prostate size, and lipid profile modifications.
Testosterone is produced by Leydig cells and has an effect on the body through binding to androgen receptors. Testosterone controls muscular growth and protein expression, as well as the voice, genitalia, and temperament. As a result, men with low testosterone levels frequently report decreased libido, exhaustion, mood swings, and dysphoria. The effects of exogenous testosterone are meant to imitate those of endogenous testosterone.
Dosage guideline:
Three to four times daily.
Usually, the dosage is 3-4 capsules daily during the first 2-3 weeks, followed by a gradual decrease to 1-3 capsules daily. You must take Testosterone with a meal. Swallow the capsules whole without chewing, using some water or other fluid. Take half of the daily dose in the morning and the other half in the evening. If the daily dose is an uneven number of capsules, take the larger number in the morning. If you have the impression that the effect of Testosterone is too strong or too weak, inform your doctor immediately.
Route of administration: Orally.
Interaction:
Food allows Testosterone Undecanoate to be taken up by your body. Therefore, Testosterone must be taken with a meal. Other medicines may influence the effects of Testosterone or Testosterone may affect other medicines. You must tell your doctor or pharmacist if you are using (or intend to use) rifampicin (an antibiotic) or medicines for epilepsy or sleeplessness.
Contraindications:
Do not take Testosterone
- If you have a tumour of the prostate or the breast.
- If you are hypersensitive (allergic) to Testosterone Undecanoate or any of the other ingredients of Testosterone.
Side Effects:
In general:
- Increased sexual desire
- Fluid retention in the tissues, usually marked by swelling of ankles or feet
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In men:
- Prolonged abnormal, painful erection of the penis
- Disturbed formation of sperm
- Decreased amount of sperm with seminal discharge
In elderly men:
- Problems with passing urine
In young boys:
- Early sexual development
- Erections occurring more often than normal
- Enlarged penis
- Disturbed growth
Precautions & Warnings:
Extra supervision by a doctor is necessary in the treatment of young boys, since Testosterone suppletion may cause early sexual development and disturb growth. Extra supervision by a doctor is also necessary in the treatment of elderly men, since male hormones may increase the size of the prostate gland. Medical checks may also be necessary for some other conditions.
Therefore, tell your doctor if you have or have ever had:
- Heart disease
- Kidney disease
- High blood pressure
- Epilepsy
- Migraine headaches
- Prostatic complaints, such as problems with passing urine.
Therapeutic Class:
Male Sex hormones (Androgens)
Storage Conditions:
Keep Testosterone out of reach and sight of children. Store at 8°C-30°C. Store in the original package in order to protect from light. Do not use Testosterone after the expiry date stated on the package, sachet and blister. Keep out of the reach of children.
Manufactured by: Renata Ltd.
