Anfree Tablet

Flupentixol + Melitracen 0.50mg+10mg
Aristopharma Ltd.

৳ 50.00

1 Strip of 10 tablets

Anfree tablets are used in the situations such as: anxiety \ depression, apathy, depression is caused by psychological factors, neuroses of depression, depression that isn’t visible, anxiety and apathy accompany psychosomatic affections, depressions associated with menopause, in drinkers and drug users, dysphoria and despair are common.


Generics: Flupentixol + Melitracen

Dosage Form: Tablet.

Flupentixol and Melitracen tablet is indicated in-

  • Anxiety / Depression
  • Apathy
  • Psychogenic depression.
  • Depressive neurosses.
  • Masked depression.
  • Psychosomatic affections accompanied by anxiety and apathy.
  • Menopausal depressions.
  • Dysphoria and depression in alcoholics and drug addicts.

This consists of two well known and well proven compounds: flupentixol-a neuroleptic with anxiolytic and antidepressant properties of its own when given in small doses, and melitracen-a bipolar thymoleptic with activating properties in low doses. In combination the compounds render a preparation with antidepressant, anxiolytic and activating properties. Maximal serum concentration is reached in about 4 hours after oral administration of flupentixol and in about 4 hours after oral administration of melitracen. The biological half-life of flupentixol is about 35 hours and that of melitracen is about 19 hours. The combination of flupentixol and melitracen does not seem to influence the pharmacokinetic properties of the individual compounds.

Dosage guideline:
Once/twice daily.

Adults: Usually 2 tablets orally daily in the morning and noon. In severe cases, the morning dose may be increased to 2 tablets.

Elderly patients: 1 tablet in the morning.

Maintenance dose: Usually 1 tablet orally in the morning. In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.

Route of administration: Orally.

This tablet may enhance the response to alcohol, barbiturates and other CNS depressants. Simultaneous administration of MAO-inhibitors may cause hypertensive crises. Neuroleptics and thymoleptics reduce the antihypertensive effect of guanethidine and similar acting compounds and thymoleptics enhance the effects of adrenaline and noradrenaline.


  • The immediate recovery phase after myocardial infarction.
  • Defects in bundle-branch conduction.
  • Untreated narrow-angle glaucoma.
  • Acute alcohol, barbiturate and opiate intoxications.
  • This tablet should not be given to patients who have received an MAO-inhibitor within two weeks.
  • Not recommended for excitable or overactive patients since its activating effect may lead to exaggeration of these characteristics.

Side Effects:
In the recommended doses side effects are rare. These could be transient restlessness and insomnia.

Pregnancy & Lactation:
This tablet should preferably not be given during pregnancy and lactation.

Precautions & Warnings:
If previously the patient has been treated with tranquillizers with sedative effect these should be withdrawn gradually.

Therapeutic Class:
Combined anxiolytics & anti-depressant drugs.

Storage Conditions:
Store at a temperature not exceeding 30°C. Keep in a dry place, away from light and heat. Keep out of the reach of children.

Manufactured by: Aristopharma Ltd.