Ansulin N Injection

Insuline Human [Long-Acting] 100IU/ml
Square Pharmaceuticals Ltd.

৳ 415.00

1 Vial of 10 ml

Treatment of all type 1 diabetic patients. Treatment of type 2 diabetic patients who are not properly regulated as formulas and / or oral hypoglycemic agents.

For the initial stabilization of diabetes during periods of stress such as severe infections and major surgery in patients with diabetic nephropathy, hyperosmolar non-ketone syndrome and diabetic patients. Treatment of gestational diabetes.


Generics: Insulin Human [rDNA] + Isophane Insulin Human

Dosage Form: Insulin.

Treatment of all type 1 diabetic patients. Treatment of type 2 diabetic patients who are not properly regulated as formulas and / or oral hypoglycemic agents.

Human insulin (rDNA) is human insulin produced using recombinant DNA technology. It is similar in structure and function to natural insulin. Insulin regulates glucose metabolism and stimulates the liver, muscle, and adipose tissue to digest and utilize glucose. It also lowers blood sugar by accelerating glycogenesis and inhibiting gluconeogenesis.

Human insulin (rDNA) 30/70 and human insulin (rDNA) 50/50 begin to work within 30 minutes of injection, peak within 28 hours, and last about 24 hours.

Dosage guideline:
Once daily.

The average range of total daily insulin requirement for maintenance therapy in type 1 diabetic patients lies between 0.5 and 1.0 IU/kg. In pre-pubertal children it usually varies from 0.7 to 1.0 IU/kg, whereas in insulin resistant cases, e.g. during puberty or due to obesity, the daily insulin requirement may be substantially higher. Initial dosages for type 2 diabetic patients are often lower, e.g. 0.3 to 0.6 IU/kg/day.

The dosage form, the dosage and the administration time of the insulin are different due to the individual differences of each patient. In addition, the dosage is also affected by food, working style and exercising intensity. Therefore, patients should use the insulin under doctor’s instruction.

An injection should be followed by a meal or snack containing carbohydrates within 30 minutes. Injection is administered subcutaneously in the upper arm, thigh, buttock or abdominal wall. A subcutaneous injection into the abdominal wall results in a faster absorption than from other injection sites. Insulin Human (rDNA) 30/70 & Insulin Human (rDNA) 50/50 are never to be administered intravenously.

Preparation before use:

Clean your hands.

Shake or rotate the vial gently to mix the solution uniformly and check if the insulin has the normal appearance.

In case of using a new vial, flip off the plastic protective cap and wipe the rubber plug with an alcohol swab.

Draw air into your syringe equal to the amount of insulin needed.

Puncture the needle into the vial and inject the air.

Turn the bottle and syringe upside down and withdraw correct dose of insulin into the syringe.

Before pulling out the needle, check if there are any bubbles remain in the syringe. If so, put the syringe upright and tap the syringe to discharge the air bubbles.

Injection site:

Choose the area where skin is less tight, such as the upper arm, thigh, buttock or abdomen.

To avoid tissue damage, choose a site for each injection that is at least 1 cm from the previous injection site.

Injection method:

Cleanse the skin with alcohol where the injection is to be made.

Put the needle in such a position as to form 45° angle with the skin.

Puncture the needle into skin and inject insulin.

Keep the needle under the skin for at least 6 seconds to make sure the entire dose is injected.

Pull the needle out and apply gentle pressure over the injected site for several seconds.

Do not rub the injection site.

Route of administration: Orally.

When using oral contraceptives, adrenocorticotropic hormone, thyroid hormone, etc., drugs that can increase blood sugar; You may need to increase your insulin intake. When using drugs with hypoglycemic activity, salicylate, sulfanilamide and other antidepressants, which will lower blood sugar, the dose of insulin should be reduced.

Hypoglycemia or the patients who have allergic reaction to insulin or any of the excipients.

Side Effects:
Hypoglycemia is the most common adverse reaction during insulin treatment, and symptoms of hypoglycemia can appear suddenly. There are few reports of allergic reactions such as redness and itching. It usually disappears after a few days. In some cases, allergies may be due to reasons other than insulin, such as disinfectants and poor injection techniques.

Pregnancy & Lactation:
Since insulin does not cross the placental barrier, there are no restrictions on the treatment of diabetes with pregnancy insulin. Insulin treatment in nursing mothers poses no risk to the baby.

Precautions & Warnings:
Insufficient medication or stopping, especially in type 1 diabetes, can lead to hyperglycemia. Hypoglycemia can occur if the insulin dose is too high for the insulin requirements. Skipping meals or exercising strenuously and unplanned can lead to low blood sugar.

Therapeutic Class:
Medium Acting Insulin

Storage Conditions:
Store at 2°C – 8°C in a refrigerator. Do not freeze. In case of insulin for recent use need not be refrigerated, try to keep it in a cool place and keep away from heat and light. The insulin in use can be kept under the room temperature for a month.

Manufactured by: Square Pharmaceuticals Ltd.