Antrenex Tablet

Oxyphenonium Bromide 5mg
Opsonin Pharma Ltd.

৳ 13.00

1 Strip of 10 tablets

Oxyphenonium is used to treat spasms and hypermotility in the gastrointestinal tract, cardiospasm, esophageal spasm, gastroduodenitis, spastic constipation, pylorospasm, peptic ulcer, and spasm associated with cancer. Biliary tract pain and spasms Urinary tract pain and spasms.


Generics: Oxyphenonium Bromide

Dosage Form: Tablet.

Oxyphenonium is indicated in Gastro-intestinal spasm and hypermotility, cardiospasm, esophagospasm, gastroduodenitis, spastic constipation, pylorospasm, peptic ulcer, spasm associated with carcinoma. Pain and spasm of the biliary tract. Pain and spasm of the urinary tract.

Oxyphenonium is an anticholinergic medicine, which means it decreases the action of acetylcholine, a substance produced by neurons that activates muscles, by inhibiting acetylcholine receptors on smooth muscle (a type of muscle). It has a direct calming effect on smooth muscle as well. Oxyphenonium is used to treat or prevent spasms in the gastrointestinal muscles caused by irritable bowel syndrome. Oxyphenonium also slows gastrointestinal propulsive motility, reduces stomach acid production, and regulates excessive pharyngeal, tracheal, and bronchial secretions.

Dosage guideline:
Four times in daily.

Average adult dosage is 10 mg (2 tablets) 4 times daily for several days. Dosage may be reduced depending on patient’s response or as directed by the physician.

Route of administration: Orally.

Reduced gastric motility interferes with absorption of other drugs. Effects potentiated by other antimuscarinics including amantadine, some antihistamines, phenothiazines and TCA.

Glaucoma, obstructive uropathy (for example, bladder neck obstruction due to prospective hypertrophy), obstructive disease of the gastrointestinal tract (as in achalasia, paralytic ileus, pyloroduodenal stenosis, etc.), intestinal atony of the elderly or debilitated patient, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis, toxic megacolon, complicating ulcerative colitis, myasthenia gravis, hypersensitivity.

Side Effects:
Common side effects are dryness of mouth, headache, palpitations, etc.

Pregnancy & Lactation:
Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Precautions & Warnings:
Children; elderly; benign prostatic hyperplasia; acute MI, cardiac failure, hypertension, thyrotoxicosis; pregnancy and lactation; fever; angle-closure glaucoma.

Therapeutic Class:
Anticholinergics (antimuscarinics)/ Anti-spasmodics

Storage Conditions:
Keep below 30°C temperature. Keep in a dry place, away from light and heat. Keep out of the reach of children.

Manufactured by: Opsonin Pharma Ltd.