Betson Ointment

Betamethasone Dipropionate 0.05%
Opsonin Pharma Ltd.

৳ 48.00

1 Tube of 20 gm

Betamethasone Dipropionate cream and ointment is indicated for the relief of the inflammatory and pruritic manifestations of resistant or severe corticosteroid-responsive dermatoses. These include- Atopic eczema, nummular eczema, contact dermatitis, neurodermatitis,  anogenital and senile pruritus, lichen planus, psoriasis.


Generics: Betamethasone Dipropionate

Dosage Form: Ointment.

Betamethasone Dipropionate cream and ointment is indicated for the relief of the inflammatory and pruritic manifestations of resistant or severe corticosteroid-responsive dermatoses. These include-

  • Atopic eczema
  • Nummular eczema
  • Contact dermatitis
  • Neurodermatitis
  • Anogenital and senile pruritus
  • Lichen planus
  • Psoriasis

Betamethasone Dipropionate is an anti-inflammatory, anti-pruritic, and vasoconstrictive topical corticosteroid. Lipocortin peptides are produced by betamethasone dipropionate. Phospholipase A2, an enzyme that induces the breakdown of leukocyte lysosomal membranes and the release of arachidonic acid, is inhibited by lipocortins. Endogenous inflammatory mediators such as prostaglandins, kinins, and histamine are formed and released less as a result of this action.
Betamethasone Dipropionate can be absorbed via normal intact skin, according to pharmacokinetics. Corticosteroids have variable degrees of binding to plasma proteins. Corticosteroids are mostly processed in the liver. The kidneys excrete lt.

Dosage guidelines:
Twice daily.
Apply a thin film once or twice daily to cover completely the affected area. Patients with chronic psoriasis who have achieved at least a marked improvement in their psoriatic lesion (i.e., approximately 80% improvement) with Betamethasone Dipropionate may be maintained in remission with a pulse dosing regimen consisting of three consecutive applications of up to 3.5 g each of Betamethasone Dipropionate cream and ointment, twelve hours apart (e.g., morning, evening, following morning) to the previously affected areas once each week. For this purpose, Betamethasone Dipropionate cream and ointment should be applied to the lesion sites previously affected and treated. Patients on this pulse dose regimen who relapse should be reverted back to the conventional dosing regimen.

Route of administration: Topically

There is no evidence of any kind of interaction.

Hypersensitivity to Betamethasone Dipropionate, other corticosteroids, or any of the preparation’s ingredients. Betamethasone Dipropionate, like other topical corticosteroids, is contraindicated in viral skin infections including vaccinia, varicella, and Herpes simplex, as well as TB, acne rosacea, fungal skin infections (moniliasis), perioral dermatitis, and ulcerative diseases.

Side Effects:
The most frequent side effects reported with Betamethasone Dipropionate are mild to moderate transient burning/stinging, dry skin, pruritus, irritation and folliculitis. Rarely reported adverse effects include tingling, prickly skin/tightening or cracking of skin, warm feeling,laminar scaling and perilesional scaling,follicular rash, skin atrophy, erythema, urticaria, vesiculation, telangiectasia, acneiform papules and hyperaesthesia.
Adverse reactions reported with the use of the Betamethasone Dipropionate ointment pulse dose regimen were mild intermittent hypertension and paraesthesia. Other local adverse reactions that have been reported with the use of topical corticosteroids include: itching, hypertrichosis, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, striae, miliaria and exacerbation of untreated infections

Pregnancy & Lactation:
No data found.

Precautions & Warnings:
Because of the danger of glaucoma and cataracts, Betamethasone Dipropionate should not be used in or near the eyes. If irritation or sensitization develops as a result of using Betamethasone Dipropionate, the medication should be stopped and appropriate therapy started. If an infection is present, an appropriate antifungal or antibacterial treatment should be given. Betamethasone Dipropionate should be stopped until the infection has been properly controlled if a favorable response does not occur quickly.

Because corticosteroids are known to be absorbed through the skin, the likelihood of systemic effects should be considered in patients receiving long-term or substantial topical treatment. Betamethasone Dipropionate should not be used under occlusive dressings since it will increase the corticosteroid’s systemic absorption. The napkin can act as an occlusive dressing in infants, increasing absorption. When applying topical corticosteroids in patients with stasis dermatitis and other skin conditions with reduced circulation, appropriate precautions should be performed. The use of topical corticosteroid treatments for an extended period of time might cause striae or atrophy of the skin and subcutaneous tissue.

Therapeutic Class:

Storage Conditions:
Store in a cool & dry place, protected from light. Keep all medicines out of reach of children.

Manufactured by: Opsonin Pharma Ltd.