Description
Generics: Ambroxol Hydrochloride
Dosage Form: Syrup.
Indications:
- Productive cough
- Acute and chronic inflammatory disorders of upper and lower respiratory tracts associated with viscid mucus including acute and chronic bronchitis
- Inflammatory disease of rhinopharyngeal tract (laryngitis, pharyngitis, sinusitis and rhinitis) associated with viscid mucus
- Asthmatic bronchitis bronchial asthma with thick expectoration
- Bronchiectasis
- Chronic pneumonia etc.
Pharmacology:
Ambroxol is the dynamic metabolite of bromhexine and it has been demonstrated that this metabolite has a more prominent bronchosecretolytic impact than bromhexine. It makes strides sputum rheology by hydrating component driving to liquefaction of bodily fluid within the lumen of respiratory tract, in this way encouraging expectoration of bodily fluid and lessening dyspnea. It invigorates generation of phospholipids of surfactant by alveolar cells, in this way contributing to the lowering of shallow pressure within the alveoli. It moreover diminishes bronchial hyperactivity. Ambroxol has hostile to provocative properties owing to the inhibitory impact on the generation of cellular cytokines and arachidonic corrosive metabolites. In patients with COPD it customarily progresses aviation route patency.
Dosage guidelines:
Advised by physician
Syrup:
- 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
- 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
- 10 years and adults: 10 ml (2 teaspoonful) 3 times a day.
Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily.
Route of administration: Orally.
Interaction:
Antitussives (e.g. Codeine) should not be taken with Boxol 100 ml because phlegm that has been dissolved by Ambroxol may not be expectorated.
Contraindications:
Contraindicated in known touchiness to Ambroxol or Bromhexine.
Side Effects:
Gastrointestinal side effects such as epigastric discomfort and a sense of stomach overfilling may occur on occasion. Allergic reactions such as eruption, urticaria, and angioneurotic edema have been observed on rare occasions.
Pregnancy & Lactation:
Boxol 100 ml has been found to have no teratogenic or fetal toxicity in tests. It is not recommended for use during pregnancy, especially during the first trimester. It is yet to be determined whether or not it is safe to use during lactation.
Precautions & Warnings:
Boxol 100 ml ought to be given cautiously to patients with gastric and duodenal ulceration or convulsive disarranges. Patients with hepatic and renal inadequate ought to take it with caution.
Therapeutic Class:
Cough expectorants & mucolytics.
 Storage Conditions:
Store in a cool & dry place, protected from light. Keep all medicines out of reach of children.
Manufactured by:Â Opsonin Pharma Ltd.
