Description
Generics:
Calcium Dobesilate + Lidocaine HCl + Dexamethasone Acetate
Dosage Form: Ointment.
Indications:
Internal and external hemorrhoids, as well as anal pruritus, are treated with this rectal ointment.
- Anal eczema is a type of dermatitis that affects the
- Acute hemorrhoidal thrombosis Anitis Perianitis
- Fissure in the anal region
- In situations of hemorrhoidectomy, there is preoperative and postoperative care.
Pharmacology:
Calcium Dobesilate regulates the compromised physiological functions of capillary walls, such as increased permeability and decreased resistance, as well as distinct symptoms of inflammation. It also possesses antithrombotic properties. A local anesthetic called lidocaine hydrochloride helps to ease discomfort. Dexamethasone Acetate is a topical Corticosteroid with anti-inflammatory and antipruritic properties.
Dosage guideline:
2-3 times daily.
Apply in the morning and bedtime and if possible after defecation. If the ointment is preferred, use the applicator by screwing it to the tube. Insert the applicator as deep as possible in the anus then press the tube gently while withdrawing it. In this case, the tube is sufficient for 8 applications. In case of external hemorrhoids or anal pruritus, apply a thin layer of the ointment several times a day. The duration of the treatment is generally of some days. The doctor must be informed if, after 1 to 2 weeks of treatment, the symptomatology has not improved or has worsened.
Calcium Dobesilate, Lidocaine HCI & Dexamethasone Acetate Ointment should be applied 2-3 times daily preferably in the morning and at bedtime, if possible apply after defecation. In the case of internal hemorrhoids apply the ointment by the applicator. In cases of external hemorrhoids and anal pruritus, apply a thin layer of the ointment several times a day. The duration of the treatment is generally of some days. The physician must be informed if, after 1 to 2 weeks of treatment the symptomatology has not improved or has worsened.
Method of use of this ointment:
For internal use-
- Before use remove the cap from the tube.
- Pierce the tube membrane by inverting the cap.
- Attach the applicator (supplied) to the tube.
- Squeeze the tube to fill the applicator and lubricate the tip with ointment for smooth insertion.
- Insert the applicator gently and to full extend into the anus and squeeze once again from the end of the tube to force the required amount of ointment into the anal canal.
- Remove the applicator after application and discard it.
- Try not to have defecation for a couple of hours after an internal application.
For external use-
- Squeeze the tube of ointment and apply a small amount to the finger.
- Apply the ointment around the outside of the anus with a finger.
- Wash the hands thoroughly with warm water and soap after each application.
- Reattach the cap to tube.
Route of administration: Topically.
Interaction:
No data found.
Contraindications:
Hypersensitivity towards the components of Pilosol.
Side Effects:
Modifications in intestinal transit, transient burning sensations, and local pain have all been recorded in extremely uncommon situations. Hypersensitivity reactions can develop, along with skin reactions and/or fever. These reactions could be allergic in nature, in which case the medication must be stopped.
Pregnancy & Lactation:
Studies in pregnant women or animals are not available and in humans, it is not known whether Calcium Dobesilate crosses the placental barrier. On the other hand, after topical administration, Lidocaine Hydrochloride and Dexamethasone Acetate are resorbed in variable quantities and can have systemic effects. Moreover, both substances cross the placental barrier. In these conditions, Pilosol should be administered during pregnancy only if the potential benefit justifies the potential risk to the fetus.
After oral administration, Calcium Dobesilate is excreted in the maternal milk in low amounts but it is not known whether this is the case with local use. After topical administration, Lidocaine Hydrochloride and Dexamethasone Acetate are excreted in the maternal milk. As a precaution, it should be decided between discontinuating the treatment or the breast-feeding.
 Precautions & Warnings:
This rectal ointment should not be used for prolonged periods of time if you have renal insufficiency. Long-term therapies should be avoided.
Therapeutic Class:
Drugs used in Ano-rectal region
Storage Conditions:
The ointment must be stored in a cool, dry place. It should be kept at a temperature below 30°C.
Manufactured by: UniMed UniHealth Pharmaceuticals Limited
