Description
Generics:
Vitamin C [Ascorbic acid]
Dosage Form: Tablet
Indications:
- Prevents & treats scurvy
- Helps in healing wounds & broken bones
- Helps to form collagen in connective tissues
- Aids in iron absorption & helps to treat anemia
- Contributes in production of hemoglobin & red blood cell in bone marrow
- Aids in preventing many types of viral and bacterial infections and potentiates the immune system
- Aids in the treatment & prevention of the common cold
- Promotes healthy capillaries, gums & teeth
Pharmacology:
This is a preparation of Ascorbic Acid (Vitamin C). Ascorbic Acid is an essential nutrient, which means it cannot be produced by the body and therefore must be obtained from diet or supplements. Ascorbic Acid has many important functions. It is required for tissue growth & repair, Adrenal gland function, enhanced immunity & healthy gums. As an antioxidant, it gives protection against harmful pollution, infection & reduces cellular damage. As a coenzyme, it is a necessary factor for wound healing, drug metabolism & metabolism of cholesterol & folic acid. As an essential nutrient, vitamin C supports healthy hair & skin, strengthens the immune system and maintain overall good health.
Dosage guideline:
- For the prevention of scurvy: 1 tablet daily
- For the treatment of scurvy: 1-2 tablets daily; but dose may be increased depending on the severity of the condition.
- For the reduction of risk of stroke in the elderly: 1-2 tablets daily.
- In other cases: 1 tablet daily or as directed by the physician.
- Maximum safe dose is 2000 mg daily in divided doses.
Route of administration: Orally
Interaction:
Potentially hazardous interactions: Ascorbic acid is incompatible in solution with aminophylline, bleomycin, erythromycin, lactobionate, nafcillin, nitrofurantoin sodium, conjugated oestrogen, sodium bicarbonate, sulphafurazole diethanolamine, chloramphenicol sodium succinate, chlorthiazide sodium and hydrocortisone sodium succinate.
Useful interactions: Ascorbic acid increases the apparent half-life of paracetamol and enhances iron absorption from the gastrointestinal tract.
Side Effects:
Ceevit has little toxicity and only mega-doses of Ceevit may cause diarrhoea, abdominal bloating, iron over-absorption that is harmful in patients with thalassaemia, sideroblastic anemia, and haemochromatosis; hyperoxaluria, hyperuricosuria, and hemolysis in patients with glucose-6 phosphate dehydrogenase deficiency. A pregnant woman taking more than 5 gm/day may suffer fetal abortion.
 Pregnancy & Lactation:
The drug is safe in normal doses in pregnant women, but a daily intake of 5 gm or more is reported to have caused abortion. The drug may be taken safely during lactation.
 Precautions & Warnings:
Ingestion of megadose (more than 1000 mg daily) of Ceevit during pregnancy has resulted in scurvy in neonates. Ceevit in mega-doses has been contraindicated for patients with hyperoxaluria. Ceevit itself is a reactive substance in the redox system and can give rise to false positive reactions in certain analytical tests for glucose, uric acid, creatine and occult blood.
 Therapeutic Class:
Vitamin-C Preparations
 Storage Conditions:
Should be stored in a dry place below 30ËšC.
Manufactured by: Square Pharmaceuticals Ltd.
