Dosage Form: Syrup.
Dicycloverine is indicated in:
- Functional bowel/irritable bowel syndrome
- Urinary incontinence secondary to unstable detrusor muscle
- Infantile colic
- GIT spasm
- Colicky abdominal pain
- Abdominal colic
Dicycloverine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically, it is [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride. Dicycloverine relieves smooth muscle spasm of the gastrointestinal tract. Dicycloverine HCl Injection is a sterile, pyrogen-free, aqueous solution for intramuscular injection (Not For Intravenous Use). It works at specific receptors, called cholinergic (or muscarinic) receptors, located on the involuntary muscle in the walls of the gut. By binding to these receptors dicycloverine prevents certain chemicals produced by the body from interacting with these receptors. This causes the gut muscle to relax, relieving the pain of colic produced by gut muscle contraction and spasm.
For oral dosage forms:
- Adults:10 to 20 mg three times a day.
- Children over 6 months of age: 5 to 10 mg three times a day.
For injectable dosage form:
- Adults: Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses).
Oral dicycloverine Hydrochloride should be started as soon as possible and the intramuscular form should not be used for periods longer than 1 or 2 days.
Children: Dose must be determined by the doctor.
Route of administration: Orally.
A sleeping disorder, mydriasis, cycloplegia, expanded visual pressure, urinary reluctance, palpitations, dyspnea.
Pregnancy Category B. Dicycloverine was not one or the other teratogenic nor embryocidal in creature trial. It, like other drugs ought to be utilized amid pregnancy as it were on the off chance that clearly required. There are no information on the emission of this sedate into breast drain. Dicycloverine ought to be utilized cautiously in case of lactating mother.
Utilize with caution in patients with autonomic neuropathy, hepatic or renal malady, ulcerative colitis, coronary heart illness, congestive heart disappointment, cardiac tachyarrhythmia, hiatal hernia, known or suspected prostatic hypertrophy.
Pregnancy & Lactation:
Pregnancy Category B. Dicycloverine was not one or the other teratogenic nor embryocidal in creature trial. It, like other drugs ought to be utilized amid pregnancy as it were on the off chance that clearly required. There are no information on the emission of this medicate into breast drain. Dicycloverine ought to be utilized cautiously in case of lactating mother.
Precautions & Warnings:
In patients with epilepsy (avoid if poorly controlled, discontinue if convulsions develop), concurrent electroconvulsive therapy (prolonged seizures reported with fluoxetine), history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase bleeding risk, and history of bleeding disorders, SSRIs should be used with caution.
Anticholinergics (antimuscarinics)/ Anti-spasmodics
Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.
Manufactured by: Square Pharmaceuticals Ltd.