Description
Generics:
Dicycloverine
Dosage Form:
Indications:
Dicycloverine is used to treat the following conditions:
- Irritable bowel syndrome/functional bowel syndrome
- Urinary incontinence as a result of a weakened detrusor muscle
- Infantile colic
- GIT spasm
- Colicky abdominal pain
- Diverticulitis
- Abdominal colic
Pharmacology:
Antispasmodic and anticholinergic (antimuscarinic) dicycloverine hydrochloride [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride is the chemical name. Dicycloverine helps to alleviate gastrointestinal smooth muscle spasms. Dicycloverine HCl Injectable is a sterile, pyrogen-free intramuscular injection solution (Not For Intravenous Use). It acts on cholinergic (or muscarinic) receptors found on the involuntary muscle of the gut walls. Dicycloverine inhibits some substances generated by the body from interacting with certain receptors by attaching to them. This relaxes the gut muscle, reducing the discomfort of colic caused by contraction and spasm of the gut muscle.
Dosage guideline:
For oral dosage forms:
- Adults:10 to 20 mg three times a day.
- Children over 6 months of age: 5 to 10 mg three times a day.
For injectable dosage form:
- Adults: Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses).
Oral dicycloverine Hydrochloride should be started as soon as possible and the intramuscular form should not be used for periods longer than 1 or 2 days.
Children: Dose must be determined by the doctor.
Route of administration: Orally.
Interaction:
These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
- ANTICHOLINERGICS; OPIOIDS/ELUXADOLINE
- ANTICHOLINERGICS/ZONISAMIDE
- ANTICHOLINERGICS/CLOZAPINE
- ANTICHOLINERGICS/SECRETIN
- AGENTS AFFECTING GROWTH HORMONE/MACIMORELIN
- ANTICHOLINERGICS/SOLID ORAL POTASSIUM CAPSULES
- ANTICHOLINERGICS/SOLID ORAL POTASSIUM TABLETS
Contraindications:
No data found.
Side Effects:
Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea.
Pregnancy & Lactation:
Pregnancy Category B. Dicycloverine was neither teratogenic nor embryocidal in animal trial. It, like other drugs should be used during pregnancy only if clearly needed. There are no data on the secretion of this drug into breast milk. Dicycloverine should be used cautiously in case of lactating mother.
 Precautions & Warnings:
Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, hiatal hernia, known or suspected prostatic hypertrophy.
Therapeutic Class:
Anticholinergics (antimuscarinics)/ Anti-spasmodics
Storage Conditions:
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Manufactured by: Square Pharmaceutical Ltd.
